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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESR2
All Species:
16.67
Human Site:
T73
Identified Species:
40.74
UniProt:
Q92731
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92731
NP_001035365.1
530
59216
T73
E
G
G
P
G
R
Q
T
T
S
P
N
V
L
W
Chimpanzee
Pan troglodytes
XP_001170268
530
59089
T73
E
G
G
P
G
R
Q
T
T
S
P
N
V
L
W
Rhesus Macaque
Macaca mulatta
Q9TTE5
279
31087
Dog
Lupus familis
XP_537473
549
61059
T92
E
G
G
P
S
R
Q
T
T
S
P
N
V
L
W
Cat
Felis silvestris
Mouse
Mus musculus
O08537
530
58994
T73
E
G
G
P
V
R
Q
T
A
S
P
N
V
L
W
Rat
Rattus norvegicus
Q62986
530
59134
S73
D
G
G
P
V
R
L
S
T
S
P
N
V
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511889
566
62507
G101
V
R
P
A
A
S
P
G
I
S
W
P
T
P
G
Chicken
Gallus gallus
Q9PTU5
472
53421
L41
L
W
S
A
P
G
H
L
S
P
L
T
L
H
C
Frog
Xenopus laevis
P81559
586
66062
V104
N
V
P
P
S
P
V
V
F
L
A
K
L
P
Q
Zebra Danio
Brachydanio rerio
P57717
569
62828
Q76
M
F
A
P
S
S
P
Q
L
S
P
Y
L
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
51.7
85.9
N.A.
88.4
88.3
N.A.
64.6
69.8
44.2
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
52.4
90.7
N.A.
93.2
93.4
N.A.
73.8
78.1
62.9
59.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
86.6
73.3
N.A.
6.6
0
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
6.6
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
20
10
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
50
50
0
20
10
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
0
0
0
10
10
10
10
10
0
30
50
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% N
% Pro:
0
0
20
70
10
10
20
0
0
10
60
10
0
20
0
% P
% Gln:
0
0
0
0
0
0
40
10
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
30
20
0
10
10
70
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
40
40
0
0
10
10
0
0
% T
% Val:
10
10
0
0
20
0
10
10
0
0
0
0
50
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
50
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _